Alzheimer’s drug trial test used for 20 years appears worthless
2012 12 18

By Sherry Baker | NaturalNews.com

What if a test of thinking abilities used to analyze whether Big Pharma drugs can help slow or treat Alzheimer’s weren’t actually accurate? And what if researchers had been relying on this screwed up test for decade upon decade? As amazing as it sounds, that appears to be the case.

Research led by Plymouth University Peninsula Schools of Medicine and Dentistry concludes the cognitive test used in Alzheimer’s drug trials is flawed. It’s so flawed, in fact, that it doesn’t track changes in the early stages of memory robbing Alzheimer’s disease. Why is this so extraordinarily important? Because data from this key stage is necessary to show whether or not a new drug works.

The test in question is the Alzheimer’s Disease Assessment Scale Cognitive Behavior Section (ADAS Cog). Developed back in the 1980s, it’s made up of 11 component parts including memory tests, language skills, naming objects and responding to commands. Patients are scored on each section resulting in a single overall score. The lower the total score, the better their cognitive performances are supposed to be. Until now, the ADAS Cog test was considered sort of a "gold standard" for assessing changes in thinking abilities as Alzheimer’s supposedly starts to destroy a person’s memory.

But the new research, published as two studies in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, which investigates the role of the test, questions its effectiveness. The results show that the assumed-accurate-for-decades ADAS Cog doesn’t work to track changes in the early stages of Alzheimer’s. Based on their findings, the Plymouth-based research team is calling for urgent changes to the ADAS Cog test. They are also not ruling out the possible need to throw the whole thing out and start over with a new test, either.

"It is impossible to say precisely the extent to which the ADAS Cog’s flaws have undermined the numerous clinical trials in which it has been used," Professor Jeremy Hobart, who headed the study, said in a media statement.

"It has been used, unchanged, for many years and its apparent contribution to suboptimal trials has led a number of drug companies to rethink their strategies. However, it is very clear that in its current form the ADAS Cog underestimates cognitive differences between people and changes over time," Hobart added. "To determine if treatments, developed from painstaking years of research, work in expensive studies we need to invest in developing measurement instruments that are fit for purpose. This requires the routine use of different methods. In its current form, the ADAS Cog is not working in people with mild Alzheimer’s disease."

While the drug companies have made little progress coming up with ways to halt or reverse Alzheimer’s disease, there is research that suggests natural health approaches can help. For example, as Natural News has previously covered, scientist William B. Grant, PhD, of the Sunlight, Nutrition, and Health Research Center (SUNARC) has come up with a hypothesis about the cause of mind-robbing Alzheimer’s disease and other vascular dementias: vitamin D deficiency.

Sources:

http://www.eurekalert.org/pub_releases/2012-12/uop-fia121412.php
http://www.naturalnews.com/026392_Vitamin_D_Alzheimers_disease.html
http://www.naturalnews.com/Alzheimers.html



Article from: naturalnews.com



Related Articles
Coconut Oil Touted as Alzheimer’s Remedy
GPS shoes for Alzheimer’s patients
Curry may prevent Alzheimer’s disease expert says
Earliest signs of Alzheimer’s found in 20-something year olds. Provides hints for prevention treatments


Latest News from our Front Page

Australian Government Pushing ‘Internet Tax’ To Pay For NSA Style Spying
2014 07 29
Forcing private companies to become mass surveillance hubs The Australian government is pushing to implement a ”surveillance tax” on the people of the country in order to pay for a mandate that would see communications companies retaining data on customers for two years. In a disturbing development that should serve as a warning to Americans, the Australian Attorney-General admitted that the surveillance ...
Japanese leader proposes first-ever ’Robot Olympics’
2014 07 29
Nations of the world will be sending their most talented athletes to Tokyo in 2020 for the Olympic Games – but if Japanese Prime Minister Shinzo Abe gets his way, they might also be pitting robots against each other. Abe announced his vision while touring robotics factories in Tokyo and Saitama, which is located just north of the country’s capital. According ...
Israel Student Union Set Up “War Room” to Sell Gaza Massacre on Facebook
2014 07 29
This article was published on July 14, 2014. The death toll in Gaza as of today, July 23, 2014, reaches 678 according to Al-Akhbar. Students at the IDC Herzliya “war room,” seen here in a screenshot, focus on posting propaganda justifying Israel’s attack on Gaza on Facebook. As the death toll from Israel’s savage bombardment of Gaza continues to climb, Israel has ...
Swedish youth suicides hit 25-year high
2014 07 29
Last year 1,600 people in Sweden took their own lives - and for Swedes aged 15 to 24, the numbers haven’t been so high since 1989. Statistics for 2013 from Sweden’s National Board of Health and Welfare (Socialstyrelsen) found that the number of suicides had increased for the second year in a row. In 2011 there were 1,378 suicides in Sweden. The ...
Magaluf bar where British girl was filmed performing sex acts on 24 men is shut down after police investigation into video
2014 07 26
Is this what the youth in Britain and Europe is spending their their energy, money, efforts and innocence on? The young girl, pictured, was lured into performing multiple sex acts after organisers offered a free drink although she thought a holiday was on offer* Council officials launched an official investigation after the video went viral Playhouse bar in Magaluf and entertainment ...
More News »