Scientists reprogram body’s own cells to kill cancer, HIV
2013-03-26 0:00

By David Gutierrez | Natural News

In a pair of papers published in the journal Cell Stem Cell, researchers from two separate Japanese universities have successfully used a new technique to reprogram the body’s own immune cells to seek out and destroy cancer cells and HIV. The researchers hope that this technique can be developed into a practical therapy for cancer, HIV and other hard-to-treat conditions. Ideally such a therapy would be free of side effects, as it would make use of the body’s own innate immune capability.

The body naturally produces a type of immune cell, killer T lymphocytes, that possesses the ability to kill not only viral and bacterial invaders, but also to destroy certain compromised cells of the body itself, such as cancerous cells or those infected with the herpes virus. Unfortunately, killer T lymphocytes are normally very short-lived, and often fail to destroy tumors before expiring themselves (this explains why, in spite of our immune systems, we still sometimes develop cancer). Experimental therapies seeking to use the body’s own T lymphocytes to fight cancer have also often failed due to the cells’ short lifespan.

In the new studies, researchers used a group of compounds known as "Yamanaka factors," which cause cells to revert into their earlier, undifferentiated stem cell form. These stem cells are of a variety known as induced pluripotent stem cells (iPS cells), with "pluripotent" meaning that the stem cells are able to differentiate into more than one type of cell.

The researchers then allowed the iPS cells to re-differentiate back into killler T lymphocytes. They found that this "reboot" produced killer T lympocytes with much longer lifespans.

Rebooting the killer T cells

In one study, researchers from the RIKEN Research Centre for Allergy and Immunology created iPS cells from killer T lymphocytes that had developed to target melanoma skin tumors. The iPS cells then differentiated back into T lymphocytes that, strikingly, were not only able to recognize the MART-1 protein characteristic of melanoma and to produce to the anti-tumor chemical interferon ?, but also were much longer-lived than natural T lymphocytes, and remained active as anti-cancer agents for their entire extended lifespan.

[...]

Read the full article at: naturalnews.com



Related Articles
Why can’t doctors tell cancer patients the truth?
EU Releases All Data on GM Corn Linked to Cancer
Cancer cells are dormant during chemotherapy
In breakthrough, patients’ immune systems attack cancer cells


Latest News from our Front Page

Your Smartphone Could be Tracking You Every 3 Minutes, Study Says
2015-04-01 2:24
Your apps want to know where you are Smartphone apps regularly collect large amounts of data on users’ locations, sometimes as often as every three minutes, new research suggests. Researchers at Carnegie Mellon University conducted a study where they asked 23 people to use their Android smartphones normally, and tracked location data requests from each device with specially designed software, the Wall ...
Facebook accused of tracking all users even if they delete accounts, ask never to be followed
2015-04-01 2:14
A new report claims that Facebook secretly installs tracking cookies on users’ computers, allowing them to follow users around the internet even after they’ve left the website, deleted their account and requested to be no longer followed. Academic researchers said that the report showed that the company was breaking European law with its tracking policies. The law requires that users are ...
'Gay cake' bakery discriminated against client over sexual orientation, court told
2015-04-01 2:37
David Scoffield QC, acting for the bakery, said if Lee’s argument was right, a Muslim printer could not turn down a contract to print leaflets about the prophet Muhammad, an atheist could not turn down an order saying God made the world and a Roman Catholic printer could not decline making leaflets calling for the legalisation of abortion on demand. Judge ...
Gay rights groups criticize Indiana religious liberties law
2015-04-01 0:10
Editor's note: Would it be ok if a court forced a bakery operated by homosexuals, to make a cake for a Christian that says: "Homosexuality is a sin"? What would the reactions be? One way tolerance? Respecting peoples beliefs extends in all directions or in no direction. Indiana Gov. Mike Pence (R) signed a religious liberties bill into law Thursday that has been ...
Daily Show's Trevor Noah under fire for Twitter jokes about Jews and women
2015-04-01 0:01
Trevor Noah – the surprise choice to succeed Jon Stewart as high-profile host of satirical news program The Daily Show – has come under fire for a series of controversial tweets he posted before his appointment. The South African comedian – son of a Swiss-German father and half-Jewish South African mother – was criticised for having made tasteless jokes about Jews ...
More News »