Scientists reprogram body’s own cells to kill cancer, HIV
2013 03 26

By David Gutierrez | Natural News

In a pair of papers published in the journal Cell Stem Cell, researchers from two separate Japanese universities have successfully used a new technique to reprogram the body’s own immune cells to seek out and destroy cancer cells and HIV. The researchers hope that this technique can be developed into a practical therapy for cancer, HIV and other hard-to-treat conditions. Ideally such a therapy would be free of side effects, as it would make use of the body’s own innate immune capability.

The body naturally produces a type of immune cell, killer T lymphocytes, that possesses the ability to kill not only viral and bacterial invaders, but also to destroy certain compromised cells of the body itself, such as cancerous cells or those infected with the herpes virus. Unfortunately, killer T lymphocytes are normally very short-lived, and often fail to destroy tumors before expiring themselves (this explains why, in spite of our immune systems, we still sometimes develop cancer). Experimental therapies seeking to use the body’s own T lymphocytes to fight cancer have also often failed due to the cells’ short lifespan.

In the new studies, researchers used a group of compounds known as "Yamanaka factors," which cause cells to revert into their earlier, undifferentiated stem cell form. These stem cells are of a variety known as induced pluripotent stem cells (iPS cells), with "pluripotent" meaning that the stem cells are able to differentiate into more than one type of cell.

The researchers then allowed the iPS cells to re-differentiate back into killler T lymphocytes. They found that this "reboot" produced killer T lympocytes with much longer lifespans.

Rebooting the killer T cells

In one study, researchers from the RIKEN Research Centre for Allergy and Immunology created iPS cells from killer T lymphocytes that had developed to target melanoma skin tumors. The iPS cells then differentiated back into T lymphocytes that, strikingly, were not only able to recognize the MART-1 protein characteristic of melanoma and to produce to the anti-tumor chemical interferon ?, but also were much longer-lived than natural T lymphocytes, and remained active as anti-cancer agents for their entire extended lifespan.

[...]

Read the full article at: naturalnews.com



Related Articles
Why can’t doctors tell cancer patients the truth?
EU Releases All Data on GM Corn Linked to Cancer
Cancer cells are dormant during chemotherapy
In breakthrough, patients’ immune systems attack cancer cells


Latest News from our Front Page

Fukushima radiation killing children, government hiding the truth
2014 04 22
Katsutaka Idogawa, former mayor of Futaba, a town near the disabled Fukushima nuclear plant, is warning his country that radiation contamination is affecting Japan’s greatest treasure - its children. Asked about government plans to relocate the people of Fatuba to the city of Iwaki, inside the Fukushima prefecture, Idogawa criticized the move as a "violation of human rights." Compared with Chernobyl, radiation ...
Why your fingerprints may not be unique
2014 04 22
Assumption that everyone has a unique fingerprint from which they can be identified through a computer database is flawed, says Home Office expert Mike Silverman Fingerprint evidence linking criminals to crime scenes has played a fundamental role in convictions in Britain since the first forensic laboratory was set up in Scotland Yard in 1901. But the basic assumption that everyone has a ...
Asteroids cause dozens of nuclear-scale blasts in Earth’s atmosphere
2014 04 22
Asteroids caused 26 nuclear-scale explosions in the Earth’s atmosphere between 2000 and 2013, a new report reveals. Some were more powerful – in one case, dozens of times stronger – than the atom bomb blast that destroyed Hiroshima in 1945 with an energy yield equivalent to 16 kilotons of TNT. Most occurred too high in the atmosphere to cause any serious damage ...
‘Editing DNA’ to eliminate genetic conditions now a reality
2014 04 22
Scientists have employed a revolutionary genome-editing computer technique that accurately identifies one faulty genetic “letter” among billions and effortlessly repairs a genetic condition in animals, paving way for human trials. The success, by MIT in Boston, is the latest achievement in the field of genome editing that has been catapulted into the spotlight through a technology that can pinpoint genetic faults ...
EU should ’undermine national homogeneity’ says UN migration chief
2014 04 22
The EU should "do its best to undermine" the "homogeneity" of its member states, the UN’s special representative for migration has said. Peter Sutherland told peers the future prosperity of many EU states depended on them becoming multicultural. He also suggested the UK government’s immigration policy had no basis in international law. He was being quizzed by the Lords EU home affairs sub-committee ...
More News »