Artificial blood vessels made on a 3D printer may soon be used for transplants of lab-created organs.
Until now, the stumbling block in tissue engineering has been supplying artificial tissue with nutrients that have to arrive via capillary vessels.
A team at the Fraunhofer Institute in Germany has solved that problem using 3D printing and a technique called multiphoton polymerisation.
Artificial blood vessels could help those in urgent need of an organ transplant.
The findings will be shown at the Biotechnica Fair in Germany in October.
Out of thousands of patients in desperate need of an organ transplant there are inevitably some who do not get it in time.
In Germany, for instance, more than 11,000 people have been put on an organ transplant waiting list in 2011 alone.
To make sure more patients receive these life-saving surgeries, researchers in tissue engineering all over the globe have been working on creating artificial tissue and even entire organs in the lab.
But for a lab-made organ to function, it needs to be equipped with artificial blood vessels - tiny and extremely complex tubes that our organs naturally possess, used to carry nutrients.
The individual techniques are already functioning and they are presently working in the test phase”
Numerous attempts have been made to create synthetic capillaries, and the latest one by the German team seems to be especially promising.
"The individual techniques are already functioning and they are presently working in the test phase; the prototype for the combined system is being built," said Dr Gunter Tovar, who heads the BioRap project at Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart.
3D printer builds artificial tissue replacements cell by cell. Source
3D printing technology has been increasingly used in numerous industries, ranging from creating clothes, architectural models and even chocolate treats.
But this time, Dr Tovar’s team had a much more challenging printing mission.
To print something as small and complex as a blood vessel, the scientists combined the 3D printing technology with two-photon polymerisation - shining intense laser beams onto the material to stimulate the molecules in a very small focus point.
The material then becomes an elastic solid, allowing the researchers to create highly precise and elastic structures that would be able to interact with a human body’s natural tissue.
So that the synthetic tubes do not get rejected by the living organism, their walls are coated with modified biomoelcules.
Such biomolecules are also present in the composition of the "inks" used for the blood vessel printer, combined with synthetic polymers.
"We are establishing a basis for applying rapid prototyping to elastic and organic biomaterials," said Dr Tovar.
"The vascular systems illustrate very dramatically what opportunities this technology has to offer, but that’s definitely not the only thing possible."
"Surgeon Anthony Atala demonstrates an early-stage experiment that could someday solve the organ-donor problem: a 3D printer that uses living cells to output a transplantable kidney. Using similar technology, Dr. Atala’s young patient Luke Massella received an engineered bladder 10 years ago; we meet him onstage."
Left and their big fat multi-cultural lie 2014 08 30
Picture the scene; a taxi is pulled over by an officer from South Yorkshire Police who finds a half-naked 12-year-old in the back of the cab so drunk or drugged that she can hardly stand. When interviewed, the taxi driver is found to have pornographic pictures of the girl on his phone.
The officer hands back the phone and – no ...
Rotherham - Child sacrifice to diversity god 2014 08 30
It is sad to see how the once great nation of England has fallen. Britain now rivals North Korea for totalitarian control. If you are White, the wrong word can send you to jail. If you are non-White you are free to rape and kill the native British with impunity.
If Henry the VIII came back from the grave, he could ...
Hungary’s Orban Bashes Liberal Immigration Policy 2014 08 29 Hungary’s Prime Minister Viktor Orban on Monday lashed out against immigration, setting one of the main policy objectives of his next term in power after winning parliamentary elections in April.
“The goal is to cease immigration whatsoever,” said Hungary’s prime minister. “I think the current liberal immigration policy, which is considered obvious and morally based, is hypocrite,” Mr. Orban said.
At a ...
China’s “Duplitecture” Cities Mimic the World’s Greatest Architectural Hits 2014 08 29 The best knockoffs in the world are in China. There are plenty of fake designer handbags and Rolexes, but China’s knockoffs go way beyond fashion. There are knockoff Apple stores that look so much like the real thing that some employees believe they are working in real Apple stores. And then there are entire knockoff cities. There are Venices with ...
Kiev loses control of Novoazovsk, rebel troops advance in southeast Ukraine 2014 08 29 Kiev’s troops had to leave the eastern Ukrainian city of Novoazovsk to save their lives, said the country’s Security and Defense Council. The authorities admitted that self-defense forces are advancing and leading a counteroffensive in the southeast.
Along with Novoazovsk, Kiev troops have lost control over the villages of Amvrosiivka and Starobeshevo in the Donetsk Region of Eastern Ukraine.
According to Ukraine’s ...