They beat like real heart cells, but the rat cardiomyocytes in a dish at Harvard University are different in one crucial way. Snaking through them are wires and transistors that spy on each cell’s electrical impulses. In future, the wires might control their behaviour too.
Versions of this souped-up, "cyborg" tissue have been created for neurons, muscle and blood vessels. They could be used to test drugsMovie Camera or as the basis for more biological versions of existing implants such as pacemakers. If signals can also be sent to the cells, cyborg tissue could be used in prosthetics or to create tiny robots.
"It allows one to effectively blur the boundary between electronic, inorganic systems and organic, biological ones," says Charles Lieber, who leads the team behind the cyborg tissue.
Artificial tissue can already be grown on three-dimensional scaffolds made of biological materials that are not electrically active. And electrical components have been added to cultured tissue before, but not integrated into its structure, so they were only able to glean information from the surface.
Bio-scaffolds go electric
Bioengineers at Harvard University have created the first examples of cyborg tissue: Neurons, heart cells, muscle, and blood vessels that are interwoven by nanowires and transistors. Source
Lieber’s team combined these strands of work to create electrically active scaffolds. They created 3D networks of conductive nanowires studded with silicon sensors. Crucially, the wires had to be flexible and extremely small, to avoid impeding the growth of tissue. The scaffold also contained traditional biological materials such as collagen.
The researchers were able to grow rat neurons, heart cells and muscle in these hybrid meshes. In the case of the heart cells, they started to contract just like normal cells, and the researchers used the network to read out the rate of the beats.
When they added a drug that stimulates heart cell contraction, they detected an increase in the rate, indicating the tissue was behaving like normal and that the network could sense such changes.
Lieber’s team also managed to grow an entire blood vessel about 1.5 centimetres long from human cells, with wires snaking through it. By recording electrical signals from inside and outside the vessel– something that was never possible before– the team was able to detect electrical patterns that they say could give clues to inflammation, whether tissue has undergone changes that make it prone to tumour formation or suggest impending heart disease.
Britain’s MI5 Connection to Woolwich Slasher Michael Adebolajo 2013 05 25
What a difference a day makes…
People are still in a state of shock and disbelief following a recent attack branded as a ‘terrorist” event by the UK media establishment and echoed in political corridors. It seemed so random…
Aside form appearing random, the brutal Woolwich attack this past week was one of the most bizarre and strangest of its kind yet, ...
Somali reporter: Swedish journalists are more dangerous than al-Shabab 2013 05 25 This article is translated by google and slightly improved for clarification.
This short story (the tip of the iceberg) is a great example of the media climate in Sweden and the lack of proper Journalism. An extremely dangerous one sided view is constantly presented by the government subsidized media.
Swedish journalists and their lies are more dangerous than the cruel Somali terrorist ...
Germany’s Merkel shrugs aside new book about communist-era past, says she never hid anything 2013 05 25
Chancellor Angela Merkel has shrugged aside a book that suggests she may have been closer to East Germany’s communist system than previously thought, saying she’s never hidden anything.
The 58-year-old Merkel grew up in East Germany and entered politics as communism crumbled in 1989. It’s long been known that, like many, she joined the communist youth organization. She has said she ...
‘Lack of public debate on immigration caused Stockholm riots’ 2013 05 25
Mishra Mrutyuanjai raises some points that we discussed with Mikael Jalving about in our Red Ice Radio program, in January earlier this year.
Sweden should put its political correctness aside and start an open debate on immigration as it’s the only way to avoid a repeat of the Stockholm riots, Mishra Mrutyuanjai, Swedish Democrats movement member, told RT.
Stockholm is reeling as ...
Stockholm riots spread west on sixth night 2013 05 25
Comments in italics
Stockholm experienced a sixth straight night of riots early Saturday, with cars torched in several immigrant-dominated suburbs, as Britain and the United States warned against travelling to the hotspots.
Nearly a week of unrest, which spread briefly Friday night to the medium-sized city of Oerebro 160 kilometers (100 miles) west of Stockholm, have put Sweden’s reputation as an oasis ...